Bonnie L. Blazer-Yost, PhD, FAPS, is the 2025 recipient of the Cell & Molecular Section Hugh Davson Distinguished Lectureship. Her talk will focus on the role of electrolyte channels, pumps and transporters in the production of cerebrospinal fluid with an emphasis on understanding and treating hydrocephalus. This lecture will build on Hugh Davson’s pivotal role in establishing the composition, function and production of cerebrospinal fluid to explore its unknowns and new discoveries.