2020 Obesity Webinar Series 1 - Brain Circuits Driving Appetite

Dr. Lora Heisler presents why for many people is it so difficult to lose weight and yet all too easy to gain those extra pounds. She will also discuss the brain circuitry that is the master controller of body weight, such as circuits activated by the fat hormone leptin.

2020 Obesity Webinar Series 2 - Utilizing Stable Isotope Tracers In Preclinical Models Of Obesity

Dr. Marshall McCue reviews stable isotope biochemistry, standard nomenclature, unit conversions and simple calculations.

2020 Obesity Webinar Series 3 - Calories, Carbs, or Quality? What Matters Most for Body Weight

Dr. Kevin Hall presents the physiology of body weight regulation and how we adapt to various changes in diet. The total calories we consume, eating carbs versus fat and differences in diet quality—which varies with the amounts of “ultra-processed” foods we consumer—will be discussed.

2020 Obesity Webinar Series 4 - Heterogeneity and Crosstalk of Human Brown Adipose Tissue

Dr. Camilla Schéele and Dr. Christian Wolfrum discuss broader aspects of brown adipose tissue and share late-breaking research relating to the role of BAT in whole body metabolic regulation.

2020 Obesity Webinar Series 5 - Cravings and Weightlifting Squats: Technologies that Explore New Metabolic and Behavioral Research

Dr. Zhen Yan presents the mechanisms underlying adaptation to resistance exercise and Dr. Diego Bohorquez describes the role of neuropods and how nutrient sensing in the gut affects behavior.

2020 Obesity Webinar Series 6 - Mitochondrial Membrane Lipids and Respiratory Efficiency

Dr. Katsu Funai shares how his team is utilizing a sophisticated mitochondrial diagnostics platform to systematically examine the role of IMM lipids on the efficiency of each of the energy transfer processes of mitochondrial oxidative phosphorylation.

2020 Obesity Webinar Series 7 - Animal Model Selection, Study Design and Current Trends in Preclinical Obesity Research

Dr. Fred Beasley presents a broad-level overview of the factors to consider when deciding on an appropriate preclinical rodent model for studying obesity and its treatments. It will feature an overview of trends in obesity and associated illnesses, and the role of pharmacological intervention.

2020 Obesity Webinar Series 8 - Anti-Obesity Pharmacotherapy: Where are we now? Where are we going?

Dr. Ania Jastreboff discusses the current use of anti-obesity pharmacotherapy, mechanisms involved, and agents in various stages of development with considerations for next steps.

2020 Obesity Webinar Series 9 - Why Is Bariatric Surgery So Effective?

Dr. Lee Kaplan presents late-breaking research about the role of the gastrointestinal tract and gut microbiota in obesity.

2021 Science of Aging Webinar Series 1 - Targeting Biological Aging: A New Paradigm for 21st Century Medicine

Dr. Matt Kaeberlein presents recent advances in understanding the mechanisms linking biological aging to disease (geroscience) have identified interventions that directly target the molecular hallmarks of aging.

2021 Science of Aging Webinar Series 2 - The Challenges of Sarcopenia: Definition, Underlying Mechanisms, Interventions and Outcomes

Charlotte A. Peterson, PhD and Jack Guralnik, MD, PhD, MPH, present the challenges of sarcopenia. They will define the disease and provide an in-depth overview of the underlying mechanisms its pathology

2021 Science of Aging Webinar Series 3 - Experimental Muscle Mechanics in Aging and Disease

Rizwan Qaisar, MBBS, PhD presents the contributions of muscle sarcoplasmic reticulum (SR) stress and calcium dysregulation to loss of muscle mass and strength. Matthew Borkowski of Aurora Scientific Inc., presents a technical overview of the experimental equipment used in this research.

2021 Science of Aging Webinar Series 4 - Aging and Bone Health

Joy Wu, MD, PhD, presents the pathophysiology of bone loss with aging, focusing on the imbalance between bone formation by osteoblasts and bone resorption by osteoclasts. She will discuss stem cell sources of osteoblasts, anabolic signaling pathways and targeting inflammation and senescence.

2021 Science of Aging Webinar Series 5 - Quality, Quantity and Timing: Regulating Healthspan and Lifespan With Diet

Dudley Lamming, PhD, takes a deep dive into his research involving how diets can affect metabolic health and longevity, the role of calorie- and collaterally imposed fasting on the benefits of a calorie-restricted diet and examine how dietary levels of protein and branched-chain amino acids leucine, isoleucine and valine affect longevity.

2021 Science of Aging Webinar Series 6 - Malignant Brain Aging: The Formidable Link to Neurodegeneration

Suzanne de la Monte, MD, MPH, discusses the classic features of neurodegeneration and how identifying ways to reverse the switch is one of the over-arching goals of brain science directed toward prevention and treatment of neurodegenerative diseases.

2021 Science of Aging Webinar Series 7 - From “Artificial” to “Real”: What 24/7 Home Cage Monitoring Teaches Us In Pre-Clinical Neurodegenerative Disease Models

Stefano Gaburro, PhD, will present an innovative noninvasive and scalable technique called Digital Ventilated Cage (DVC).  Brun Ulfhake, MD, PhD, will show how this technique can be used to study circadian and circannual biorhythmicity of small rodents and approaches to characterize and extract metrics of the spontaneous home-cage way of life for mice.

2021 Science of Aging Webinar Series 8 - Aging and Skeletal Muscle Plasticity

Sue Bodine, PhD, FAPS, discusses the study of the neuromuscular system and its response and adaptation to various stressors, including aging. Her recent focus is identifying the cellular and molecular mechanisms that regulate skeletal muscle mass, especially under atrophy-inducing conditions.

2021 Science of Aging Webinar Series 9 - Cardiac Inflammation and Repair Following Myocardial Infarction

Merry Lindsey, PhD presents recent research that has expanded our understanding of MI LV remodeling, including recent proteomic advances focused on the ECM compartment to provide novel functional and translational insights, an overview of how cardiac ECM research has evolved and insight into future directions.

2021 Science of Aging Webinar Series10 - Cardiac Glucose Metabolism: Heart Failure in Diabetes and Aging

E. Dale Abel, MD, PhD, will present recent studies revealing novel mechanisms by which perturbed metabolism of glucose and pyruvate contribute to the pathophysiology of heart failure.

2021 Translational Discovery Series 1 - CRISPR-Enhanced Adipocyte Browning: A Cell Therapy Approach to Treat Metabolic Disease

Join Michael Czech, PhD as he discusses adipose tissue "browning" as a treatment for metabolic disease, and presents recent data using light sheet microscopy to visualize functional changes in adipose tissue depots.